Ciplar 40mg Tablet

Basic Information

• Brand Name: Ciplar 40mg Tablet

• Generic Name: Propranolol Hydrochloride

• Strength: 40 mg

• Category: Beta-Blocker (Non-Selective) / Antihypertensive

• Manufacturer: Cipla Ltd.

• Prescription Required: Yes (Rx)

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Composition

Each tablet contains:

• Propranolol Hydrochloride 40 mg

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Uses / Indications

Ciplar 40mg Tablet is prescribed for:

• Hypertension (High Blood Pressure)

• Angina (chest pain due to reduced blood supply to the heart)

• Arrhythmias (abnormal heart rhythms)

• Prevention of Migraine headaches

• Anxiety (performance anxiety, palpitations, tremors)

• Thyrotoxicosis (overactive thyroid symptoms)

• Post-heart attack care – reduces recurrence risk & improves survival

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Mechanism of Action

• Propranolol is a Non-selective Beta-Blocker.

• Blocks Beta-1 (heart) and Beta-2 (lungs, blood vessels) receptors.

• Reduces heart rate & contractility → lowers BP and cardiac workload.

• Improves oxygen supply-demand balance in the heart → relieves angina.

• Controls adrenaline-related anxiety symptoms and tremors.

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Dosage & Administration

• Usual adult dose: 40–160 mg daily (in divided doses).

• 40 mg may be given once or twice daily depending on condition.

• Take with or after food to avoid gastric irritation.

• Swallow whole with water.

• Do not stop suddenly – may cause rebound hypertension, angina, or arrhythmia.

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Side Effects

Common side effects:

• Dizziness, fatigue

• Slow heartbeat (bradycardia)

• Cold hands and feet

• Stomach upset, nausea

• Sleep disturbances, vivid dreams

Serious but rare:

• Severe low BP or heart rate

• Breathing difficulty (especially in asthma/COPD patients)

• Worsening of heart failure

• Masked low blood sugar symptoms (in diabetics)

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Precautions & Warnings

• Use with caution in patients with:

  • Asthma/COPD

  • Diabetes (may mask hypoglycemia)

  • Heart block, severe bradycardia, or heart failure

  • Liver or kidney disease

• Not safe during pregnancy or breastfeeding unless prescribed.

• Avoid alcohol (increases dizziness and drowsiness).

• Regular monitoring of blood pressure and heart rate is necessary.

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Drug Interactions

• Other antihypertensives (extra BP lowering effect)

• Antiarrhythmics (digoxin, amiodarone – risk of bradycardia)

• Insulin/antidiabetic medicines (may mask low sugar symptoms)

• NSAIDs (reduce antihypertensive effect)

• Thyroid medicines (interfere with thyroxine)

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Storage

• Store below 30°C in a dry place.

• Protect from light & moisture.

• Keep out of reach of children.