Clarithro Dry Syrup 30 ml

Basic Information

• Brand Name: Clarithro Dry Syrup 30 ml

• Type: Antibiotic (Macrolide, Pediatric Use)

• Form: Dry Syrup (for oral suspension after reconstitution)

• Pack Size: Bottle of 30 ml with measuring spoon/cup

• Manufacturer / Marketer: Abbott India Ltd. (also marketed by other companies)

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Composition (per 5 ml of reconstituted suspension)

• Clarithromycin – 125 mg
  (Some brands may also offer 250 mg/5 ml strength, but 125 mg/5 ml is common for 30 ml packs)

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Uses / Indications

Clarithro Dry Syrup 30 ml is prescribed for children (pediatric use) in conditions like:

• Respiratory tract infections – pharyngitis, tonsillitis, sinusitis, bronchitis, pneumonia

• Ear infections – otitis media

• Skin & soft tissue infections – cellulitis, impetigo, abscess

• Helicobacter pylori infection (as part of triple therapy in children, under specialist guidance)

• Mycobacterial infections in special pediatric cases (HIV/immunocompromised children)

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Mechanism of Action

• Clarithromycin (Macrolide antibiotic):

  • Binds to 50S ribosomal subunit of bacteria

  • Inhibits protein synthesis → stops bacterial growth

  • Active against Gram-positive, Gram-negative & atypical bacteria

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Dosage & Administration

• Children: Typically 7.5 mg/kg twice daily, or as per pediatrician’s advice

• Reconstitution:

  • Add boiled & cooled water up to the marked line → shake well to form uniform suspension

  • Shake well before each dose

• Administer using provided measuring spoon/cup

• Give after meals to minimize stomach upset

• Once reconstituted, use within 7–10 days; store in refrigerator if advised

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Side Effects

• Common: nausea, diarrhea, stomach pain, headache, bitter/metallic taste

• Rare: rash, liver enzyme elevation, dizziness, irregular heartbeat (QT prolongation)

• Severe (rare): persistent diarrhea (C. difficile infection)

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Precautions & Warnings

• Use strictly under pediatrician’s prescription

• Not useful for viral infections (cold, flu)

• Caution in children with liver or kidney problems

• Avoid if allergic to macrolides (erythromycin, azithromycin, clarithromycin)

• Discard leftover syrup after expiry of usage period