Cefakind-CV 325 Tablet

Basic Information

• Brand Name: Cefakind-CV 325 Tablet

• Type: Antibiotic (Cephalosporin + Beta-lactamase Inhibitor)

• Form: Tablet

• Pack Size: Strip of 6 / 10 tablets (commonly available)

• Manufacturer / Marketer: Mankind Pharma Ltd.

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Composition (per tablet)

• Cefuroxime Axetil – 250 mg

• Clavulanic Acid – 75 mg

(Total = 325 mg strength)

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Uses / Indications

Cefakind-CV 325 Tablet is prescribed for mild to moderate bacterial infections, such as:

• Respiratory tract infections: sinusitis, tonsillitis, pharyngitis, bronchitis, pneumonia

• ENT infections: ear, nose, and throat bacterial infections

• Urinary tract infections (UTI): cystitis, pyelonephritis

• Skin & soft tissue infections: cellulitis, abscess, wound infections

• Bone & joint infections

• Post-operative infections

• Mixed bacterial infections caused by resistant organisms

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Mechanism of Action

• Cefuroxime (Cephalosporin antibiotic): Inhibits bacterial cell wall synthesis, leading to bacterial death (bactericidal)

• Clavulanic Acid (Beta-lactamase inhibitor): Blocks bacterial enzymes (beta-lactamases) that make bacteria resistant to antibiotics → enhances cefuroxime’s effectiveness

• Combined Effect: Provides strong, broad-spectrum coverage against both Gram-positive & Gram-negative bacteria

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Dosage & Administration

• Adults: 1 tablet twice daily, or as prescribed by doctor

• Children (>12 years): Dose depends on weight; pediatric suspension recommended for younger children

• Should be taken after meals to improve absorption

• Duration: typically 5–14 days, depending on type and severity of infection

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Side Effects

• Common: nausea, diarrhea, abdominal pain, headache

• Rare: rash, oral thrush, dizziness, mild liver enzyme changes

• Severe (rare): allergic reactions, antibiotic-associated diarrhea (C. difficile)

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Precautions & Warnings

• Use only under doctor’s supervision

• Avoid in patients allergic to cephalosporins, penicillins, or clavulanic acid

• Use cautiously in those with kidney or liver disease

• May interact with anticoagulants (warfarin) and antacids

• Pregnant & breastfeeding women: generally safe if prescribed