Brand Name
Feburic Plus
Generic Name / Composition
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Febuxostat 40 mg / 80 mg (strength may vary by brand pack)
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Colchicine 0.5 mg
Main Category
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Anti-gout Combination (Xanthine Oxidase Inhibitor + Anti-inflammatory Agent)
Description
Feburic Plus Tablet is a fixed-dose combination of Febuxostat and Colchicine.
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Febuxostat lowers uric acid levels by inhibiting xanthine oxidase.
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Colchicine helps control inflammation and prevents painful gout flare-ups during uric acid lowering therapy.
This combination provides dual action – lowering uric acid and reducing acute attacks.
Uses / Indications
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Chronic gout management with hyperuricemia
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Prevention of gout flare-ups during uric acid-lowering treatment
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Patients not controlled by Febuxostat alone
Dosage (General Guidance)
(As prescribed by physician)
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Adults: Usually 1 tablet daily (strength depends on uric acid levels and patient profile)
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Taken with or without food
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Therapy is long-term; monitoring of uric acid levels required
Side Effects
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Nausea, vomiting, abdominal pain
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Diarrhea (mainly due to colchicine)
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Headache, dizziness
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Rash, liver enzyme changes
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Rare: Severe hypersensitivity, muscle weakness, cardiovascular events
Precautions / Warnings
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Not recommended in asymptomatic hyperuricemia
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Avoid in patients with severe liver/kidney impairment
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Colchicine should be used cautiously in elderly patients (risk of toxicity)
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May cause gout flare-ups in initial phase; additional anti-inflammatory may be required
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Avoid in pregnancy & breastfeeding unless essential
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Requires regular monitoring of uric acid and liver function
Drug Interactions
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Azathioprine & Mercaptopurine (contraindicated)
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Statins & Cyclosporine (↑ risk of muscle toxicity with Colchicine)
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Warfarin (↑ bleeding risk)
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Strong CYP3A4 inhibitors (↑ colchicine toxicity)
Packaging
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Strip of 10 tablets
Manufacturer
Marketed in India by multiple companies under license (Ajanta Pharma Ltd. is one of the key marketers).
Reviews
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