Dolo 650 Tablet

Basic Information

• Brand Name: Dolo 650 Tablet

• Type: Analgesic & Antipyretic

• Form: Tablet

• Pack Size: Strip of 15 tablets (commonly available)

• Manufacturer / Marketer: Micro Labs Ltd.

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Composition (per tablet)

• Paracetamol (Acetaminophen) – 650 mg

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Uses / Indications

Dolo 650 is prescribed for the treatment of:

• Fever (any cause – viral, bacterial, post-vaccination, etc.)

• Headache, body ache, muscle pain

• Common cold & flu-related fever

• Toothache

• Backache, arthritis pain (mild to moderate)

• Post-surgical pain & fever

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Mechanism of Action

• Paracetamol works by:

  • Blocking prostaglandin synthesis in the brain → reduces pain & inflammation

  • Acting on the hypothalamus (thermoregulatory center) → lowers fever

• Provides fast relief from fever & mild-to-moderate pain

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Dosage & Administration

• Adults: 1 tablet every 6–8 hours as needed

• Maximum: Do not exceed 4 grams per day (i.e., max 6 tablets in 24 hours)

• Should be taken after food with water

• Children: Separate pediatric formulations are recommended

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Side Effects

• Generally safe when used as recommended

• Rare: nausea, vomiting, stomach upset

• Very high doses / overdose → liver damage (hepatotoxicity)

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Precautions

• Use with caution in patients with liver disease, alcoholism, or chronic alcohol use

• Avoid taking with other medicines containing paracetamol

• Pregnant & breastfeeding women: use under medical supervision

• Keep away from children