Cardace 2.5mg Capsule

Basic Information

• Brand Name: Cardace 2.5mg Capsule

• Generic Name: Ramipril

• Strength: 2.5 mg

• Category: Antihypertensive / ACE Inhibitor

• Manufacturer: Sanofi India Ltd.

• Prescription Required: Yes (Rx)

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Composition

Each capsule contains:

• Ramipril 2.5 mg

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Uses / Indications

Cardace 2.5mg Capsule is prescribed for:

• Hypertension (High Blood Pressure) – lowers BP and prevents complications.

• Heart Failure – improves survival and reduces symptoms.

• Post-Myocardial Infarction (after heart attack) – lowers risk of recurrence.

• Prevention of stroke, kidney problems, and cardiovascular complications in high-risk patients (diabetes, chronic kidney disease, etc.).

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Mechanism of Action

• Ramipril is an ACE Inhibitor (Angiotensin-Converting Enzyme Inhibitor).

• Blocks conversion of angiotensin I to angiotensin II → prevents blood vessel constriction.

• Relaxes and widens blood vessels → lowers blood pressure.

• Reduces strain on the heart and improves circulation.

• Protects kidneys, especially in diabetic patients.

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Dosage & Administration

• Usual adult dose: 2.5–10 mg daily (single or divided dose).

• Initial dose often 2.5 mg once daily.

• Dose is adjusted based on patient’s blood pressure and response.

• Can be taken with or without food.

• Take at the same time daily.

• Do not stop suddenly without consulting a doctor.

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Side Effects

Common side effects:

• Dizziness, headache

• Dry cough (typical with ACE inhibitors)

• Fatigue, weakness

• Stomach upset

Serious but rare:

• Low blood pressure (hypotension)

• High potassium levels (hyperkalemia)

• Kidney function impairment

• Swelling of face/throat (angioedema – medical emergency)

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Precautions & Warnings

• Use cautiously in patients with:

  • Kidney or liver disease

  • Heart failure

  • Electrolyte imbalance (high potassium)

• Not safe during pregnancy or breastfeeding.

• Avoid alcohol (may worsen dizziness).

• Regular monitoring of blood pressure, kidney function, and potassium levels is important.

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Drug Interactions

• Other antihypertensives (additive effect)

• Potassium supplements / potassium-sparing diuretics

• NSAIDs (ibuprofen, diclofenac – may reduce effect & damage kidneys)

• Lithium (risk of toxicity)

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Storage

• Store below 30°C in a cool, dry place.

• Protect from moisture & sunlight.

• Keep out of reach of children.