Cefakind-CV 250 Tablet

Basic Information

• Brand Name: Cefakind-CV 250 Tablet

• Type: Antibiotic (Cephalosporin + Beta-lactamase Inhibitor)

• Form: Tablet

• Pack Size: Strip of 6 / 10 tablets (commonly available)

• Manufacturer / Marketer: Mankind Pharma Ltd.

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Composition (per tablet)

• Cefuroxime Axetil – 250 mg

• Clavulanic Acid – 125 mg

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Uses / Indications

Cefakind-CV 250 Tablet is prescribed for mild to moderate bacterial infections, such as:

• Respiratory tract infections: bronchitis, pneumonia, sinusitis, tonsillitis, pharyngitis

• Ear, Nose & Throat (ENT) infections – otitis media, sinus infections, throat infections

• Urinary tract infections (UTI): cystitis, pyelonephritis

• Skin & soft tissue infections: cellulitis, boils, abscesses, wound infections

• Bone & joint infections

• Post-surgical infections

• Mixed bacterial infections where resistance is suspected

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Mechanism of Action

• Cefuroxime (Cephalosporin antibiotic): Inhibits bacterial cell wall synthesis → causes bacterial lysis & death (bactericidal)

• Clavulanic Acid (Beta-lactamase inhibitor): Prevents breakdown of cefuroxime by resistant bacteria → enhances antibiotic effect

• Combined Effect: Effective against a wide range of resistant Gram-positive & Gram-negative bacteria

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Dosage & Administration

• Adults: 1 tablet twice daily, as prescribed

• Children (>12 years): Dose depends on weight; pediatric suspension preferred for younger children

• Should be taken after meals for better absorption

• Duration: typically 5–10 days, depending on infection type

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Side Effects

• Common: diarrhea, nausea, abdominal discomfort, headache

• Rare: rash, dizziness, oral/vaginal yeast infection

• Severe (rare): allergic reaction, antibiotic-associated diarrhea (C. difficile), liver enzyme elevation

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Precautions & Warnings

• Use only on doctor’s prescription

• Avoid in patients allergic to cephalosporins, penicillins, or clavulanic acid

• Use cautiously in patients with kidney/liver impairment

• May interact with anticoagulants (like warfarin) & antacids

• Safe in pregnancy & breastfeeding if prescribed