Generic Name: Vildagliptin 50 mg
Category: Oral Anti-Diabetic (DPP-4 Inhibitor)
Description:
Jalra 50 mg Tablet is an oral anti-diabetic medicine used to treat Type 2 Diabetes Mellitus. It contains Vildagliptin, a DPP-4 inhibitor (Dipeptidyl Peptidase-4 inhibitor), that helps improve blood sugar control in adults.
It works by increasing incretin hormone activity, which stimulates insulin release from the pancreas and reduces excess glucose production in the liver. Jalra effectively lowers both fasting and post-meal blood sugar levels, and it has a low risk of hypoglycemia when used alone.
It can be used as monotherapy (alone) or in combination with other anti-diabetic medicines like Metformin, Sulfonylureas, Thiazolidinediones, or Insulin.
Uses:
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Management of Type 2 Diabetes Mellitus in adults
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Helps prevent long-term diabetes complications like kidney damage, neuropathy, eye problems, heart attack, and stroke
Mechanism of Action:
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Inhibits the DPP-4 enzyme
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Increases levels of incretin hormones (GLP-1, GIP)
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Enhances glucose-dependent insulin secretion from pancreatic beta cells
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Reduces hepatic (liver) glucose output
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Improves overall glycemic control
Dosage & Administration:
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Standard dose: 50 mg once or twice daily, as prescribed by doctor
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Can be taken with or without food
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Dose may be adjusted if used with other anti-diabetic drugs
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Swallow whole with water
Common Side Effects:
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Headache
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Dizziness
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Stomach discomfort, constipation
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Cold or sore throat
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Fatigue
Serious Side Effects (rare):
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Pancreatitis (severe abdominal pain, nausea, vomiting)
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Allergic reactions (rash, itching, swelling, breathing difficulty)
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Liver dysfunction (yellowing of skin/eyes, dark urine)
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Joint pain (rare but reported)
Warnings & Precautions:
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Not for Type 1 Diabetes or diabetic ketoacidosis
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Use with caution in liver or kidney disease
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Risk of hypoglycemia increases when combined with insulin or sulfonylureas
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Avoid excess alcohol consumption
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Regular monitoring of blood sugar, liver function, and HbA1c is advised
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