Listril 5mg Tablet

Basic Information

• Brand Name: Listril 5mg Tablet

• Generic Name: Lisinopril

• Strength: 5 mg

• Category: Antihypertensive / ACE Inhibitor

• Manufacturer: Torrent Pharmaceuticals Ltd.

• Prescription Required: Yes (Rx)

---

Composition

Each tablet contains:

• Lisinopril 5 mg

---

Uses / Indications

Listril 5mg Tablet is prescribed for:

• Hypertension (High Blood Pressure) – helps control BP and prevent related complications.

• Heart Failure – improves heart function, reduces symptoms, and increases survival.

• Post-Myocardial Infarction (after heart attack) – lowers risk of recurrence and complications.

• Kidney protection in diabetic patients with hypertension.

---

Mechanism of Action

• Lisinopril is an ACE Inhibitor.

• Prevents conversion of angiotensin I to angiotensin II → stops narrowing of blood vessels.

• Relaxes and dilates arteries → lowers blood pressure.

• Improves blood flow, reduces workload on the heart, and protects kidneys.

---

Dosage & Administration

• Usual adult dose: 2.5–40 mg daily.

• 5 mg once daily is a common starting or maintenance dose for hypertension and heart conditions.

• Dose may be increased gradually depending on BP and clinical response.

• Can be taken with or without food.

• Should be taken at the same time every day.

• Do not discontinue without doctor’s advice.

---

Side Effects

Common side effects:

• Dizziness, headache

• Persistent dry cough

• Weakness, fatigue

• Stomach upset

Serious but rare:

• Low blood pressure (hypotension)

• High potassium levels (hyperkalemia)

• Kidney function impairment

• Angioedema (swelling of face/throat – medical emergency)

---

Precautions & Warnings

• Use carefully in patients with:

  • Kidney or liver disease

  • Heart failure

  • Electrolyte imbalance (high potassium levels)

• Not safe in pregnancy or breastfeeding.

• Avoid alcohol (may worsen dizziness).

• Regular monitoring of blood pressure, potassium, and kidney function is recommended.

---

Drug Interactions

• Other antihypertensives (stronger effect)

• Potassium supplements / potassium-sparing diuretics

• NSAIDs (ibuprofen, diclofenac – may reduce effect & harm kidneys)

• Lithium (increased toxicity risk)

---

Storage

• Store below 30°C in a cool, dry place.

• Protect from sunlight & moisture.

• Keep away from children.