Solu-Medrol Injection

Brand Name: Solu-Medrol Injection
Composition: Methylprednisolon Sodium Succinate
Dosage Form: Injection (IV/IM)
Manufacturer: Pfizer Ltd.
Category: Corticosteroid

Description: Solu-Medrol Injection contains Methylprednisolone Sodium Succinate, a fast-acting corticosteroid. It reduces inflammation, suppresses the immune response, and helps in severe allergic, autoimmune, and inflammatory conditions. It is widely used in emergency care, asthma attacks, arthritis, and certain critical illnesses.

Uses:

• Severe allergic reactions & anaphylaxis

• Asthma & COPD exacerbations

• Rheumatoid arthritis, lupus, and autoimmune diseases

• Multiple sclerosis relapses

• Severe skin diseases (eczema, psoriasis)

• Cerebral edema (brain swelling)

• Certain cancers as part of chemotherapy regimens

• COVID-19 and ARDS (as per doctor’s protocol)

Dosage & Administration:

• Adults: 10–500 mg IV/IM depending on severity; in life-threatening cases up to 1–2 g/day.

• Children: Dose individualized by weight and condition.

• Route: IV injection/infusion (preferred) or IM.
  👉 To be administered strictly under doctor’s supervision.

Side Effects: Increased blood sugar, mood changes, weight gain, fluid retention, stomach irritation, high BP, infection risk. Long-term: osteoporosis, adrenal suppression, eye problems. Rare: severe allergic reaction.

Precautions:

• Avoid in systemic fungal infections and untreated serious infections.

• Use cautiously in diabetes, hypertension, heart disease, liver/kidney impairment, peptic ulcer.

• Not recommended in pregnancy unless benefits outweigh risks.

• Taper gradually after long-term use to avoid adrenal crisis.

Drug Interactions:

• Increased bleeding risk with anticoagulants (warfarin, heparin).

• May reduce effect of vaccines.

• May increase blood sugar → caution with antidiabetic medicines.

• Risk of stomach bleeding with NSAIDs (ibuprofen, diclofenac).

Storage: Store below 25°C, protect from light & moisture. Reconstituted solution should be used immediately or as per manufacturer’s guidance. Keep away from children.