Tranexa Injection

Brand Name: Tranexa Injection
Composition: Tranexamic Acid 500 mg/5 ml
Dosage Form: Injection (IV/IM)
Manufacturer: Pfizer Ltd. (also available from other Indian pharma companies)
Category: Antifibrinolytic Agent

Description: Tranexa Injection contains Tranexamic Acid, a medicine that prevents the breakdown of blood clots by blocking plasminogen activation. It is used to control and prevent excessive bleeding in various medical and surgical conditions, including trauma, heavy menstrual bleeding, dental procedures, and after surgery.

Uses:

• Excessive bleeding after surgery or trauma

• Heavy menstrual bleeding (menorrhagia)

• Bleeding associated with tooth extraction or dental surgery

• Nosebleeds (epistaxis)

• Hereditary angioedema (as advised)

• Postpartum hemorrhage (under strict hospital monitoring)

Dosage & Administration:

• Adults: 500–1000 mg IV 2–3 times daily (dose depends on condition).

• Children: Dose individualized by weight.

• Route: Slow IV injection or IV infusion; IM use less common.
  👉 Dose and duration must be strictly as per doctor’s advice.

Side Effects: Nausea, vomiting, diarrhea, dizziness, headache, injection site reaction. Rare: visual disturbances, blood clots, allergic reactions.

Precautions:

• Avoid in patients with active thromboembolic disease (DVT, PE, stroke).

• Use with caution in kidney impairment, seizures, and patients at risk of clotting.

• Eye check-up may be required in long-term use.

• Safe in pregnancy/lactation only if prescribed.

Drug Interactions:

• Risk of clotting increases with oral contraceptives, estrogen therapy, anticoagulants.

• Avoid combination with other antifibrinolytics.

• Inform doctor about all blood-thinning or clotting-related medicines.

Storage: Store below 25°C, protect from light & moisture. Do not freeze. Keep out of reach of children.