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Zifi-O 400 Tablet

Original price was: 200.00₹.Current price is: 180.00₹.

Zifi-O 400 Tablet (Cefixime 200 mg + Ofloxacin 200 mg) is a broad-spectrum antibiotic used to treat respiratory, urinary, gastrointestinal, ENT, skin, and typhoid infections in adults.

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Category:

Brand Name

Zifi-O 400

Generic Name / Composition

  • Cefixime 200 mg (3rd Generation Cephalosporin Antibiotic)

  • Ofloxacin 200 mg (Fluoroquinolone Antibiotic)
    (Total strength per tablet: 400 mg)


Main Category

  • Antibiotic Combination (Cephalosporin + Fluoroquinolone)


Description

Zifi-O 400 Tablet is a dual-action broad-spectrum antibiotic containing Cefixime + Ofloxacin.

  • Cefixime stops bacterial growth by inhibiting cell wall synthesis.

  • Ofloxacin kills bacteria by blocking DNA gyrase, preventing replication.

This combination provides strong coverage against resistant and mixed infections.


Uses / Indications

  • Respiratory tract infections (tonsillitis, pharyngitis, bronchitis, pneumonia)

  • ENT infections (sinusitis, otitis media)

  • Urinary tract infections (UTI)

  • Gastrointestinal infections (infective diarrhea, dysentery, typhoid fever)

  • Skin & soft tissue infections


Dosage (General Guidance)

(As prescribed by physician)

  • Adults: 1 tablet twice daily (Cefixime 200 mg + Ofloxacin 200 mg)

  • Children: Not recommended; pediatric forms are preferred

  • Duration: Typically 5–10 days depending on infection

Route: Oral
Advice: Take after meals with water to minimize gastric irritation


Side Effects

  • Nausea, vomiting, stomach pain

  • Diarrhea, loose stools

  • Headache, dizziness

  • Rash, itching (allergy)

  • Rare: Tendonitis/tendon rupture (Ofloxacin-related), liver enzyme changes, severe allergic reactions


Precautions / Warnings

  • Not effective in viral infections (cold, flu)

  • Avoid if allergic to cephalosporins, penicillins, or fluoroquinolones

  • Use cautiously in kidney/liver impairment, epilepsy, or tendon disorders

  • Avoid in pregnancy & breastfeeding unless advised by doctor

  • Complete the full antibiotic course to avoid resistance


Drug Interactions

  • Antacids & iron supplements (↓ Ofloxacin absorption)

  • Warfarin (↑ bleeding risk)

  • Probenecid (↑ Cefixime concentration)

  • Corticosteroids (↑ risk of tendon rupture with Ofloxacin)


Packaging

  • Strip of 10 tablets


Manufacturer

FDC Limited
Mumbai, India

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