Aciloc 150 Injection

Brand Name: Aciloc 150 Injection
Composition: Ranitidine 150 mg
Dosage Form: Injection (IV/IM)
Manufacturer: Cadila Pharmaceuticals Ltd.
Category: (Antiulcer Agent)

Description: Aciloc 150 Injection contains Ranitidine, an H2 receptor blocker. It works by reducing the production of excess stomach acid and provides relief in acid-related disorders. It is used for gastric ulcers, duodenal ulcers, GERD, Zollinger–Ellison syndrome, and prevention of stress-induced ulcers in critically ill patients.

Uses:

• Gastric & duodenal ulcers

• Gastroesophageal reflux disease (GERD)

• Zollinger–Ellison syndrome (excess stomach acid)

• Erosive esophagitis

• Prevention of stress-induced ulcers in hospitalized patients

Dosage & Administration:

• Adults: 50 mg IV/IM every 6–8 hrs (may increase up to 150 mg/24 hrs depending on severity).

• Route: Slow IV injection, IV infusion, or IM.
  👉 Dose must be individualized by physician.

Side Effects: Headache, dizziness, constipation, diarrhea, fatigue, injection site reaction. Rare: liver dysfunction, low blood counts, cardiac arrhythmias (IV use).

Precautions:

• Contraindicated in patients allergic to ranitidine or other H2 blockers.

• Use cautiously in kidney and liver impairment (dose adjustment needed).

• Long-term use may increase risk of vitamin B12 deficiency.

• Safe in pregnancy/lactation only if prescribed by doctor.

Drug Interactions:

• May affect absorption of drugs that require acidic pH (e.g., ketoconazole, itraconazole).

• May interact with warfarin (changes INR, bleeding risk).

• Caution with high-dose NSAIDs (risk of gastric irritation).

Storage: Store below 25°C, protect from light & moisture. Use freshly prepared solution immediately. Keep out of reach of children.