Basic Information
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Brand Name: Amtas 10mg Tablet
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Generic Name: Amlodipine
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Strength: 10 mg
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Category: Antihypertensive / Calcium Channel Blocker
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Manufacturer: Intas Pharmaceuticals Ltd.
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Prescription Required: Yes (Rx)
Composition
Each tablet contains:
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Amlodipine Besylate equivalent to Amlodipine 10 mg
Uses / Indications
Amtas 10mg Tablet is prescribed for:
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Hypertension (High Blood Pressure) – when the 5mg dose is not enough.
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Angina Pectoris (chest pain due to reduced blood supply to the heart).
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Coronary Artery Disease (CAD).
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Long-term prevention of heart attack, stroke, and kidney complications linked with uncontrolled blood pressure.
Mechanism of Action
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Belongs to the class of Calcium Channel Blockers (CCBs).
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Relaxes and widens blood vessels → lowers resistance & blood pressure.
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Improves oxygen delivery to the heart muscles → prevents angina.
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Reduces workload on the heart and improves circulation.
Dosage & Administration
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Usual adult dose: 5–10 mg once daily.
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10 mg once daily is the maximum recommended dose.
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Can be taken with or without food.
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Should be taken at the same time daily.
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Do not stop suddenly without medical supervision.
Side Effects
Common side effects:
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Swelling of ankles/feet (edema)
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Headache, dizziness, flushing
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Palpitations (fast heartbeat)
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Fatigue, weakness
Serious but rare:
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Severe fall in blood pressure
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Worsening of angina during initial therapy (rare)
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Allergic reactions (rash, swelling, difficulty breathing)
Precautions & Warnings
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Use carefully in patients with:
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Severe liver disease
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Heart failure
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Low blood pressure
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Avoid alcohol (may increase dizziness).
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Pregnant & breastfeeding women: use only if prescribed.
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Can cause dizziness → avoid driving or using heavy machinery if affected.
Drug Interactions
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Other antihypertensive medicines
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Antifungals (ketoconazole, itraconazole)
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Antibiotics (clarithromycin, erythromycin)
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Grapefruit juice (may increase side effects)
Storage
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Store in a cool, dry place below 30°C.
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Keep away from sunlight & moisture.
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Keep out of children’s reach.
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