Cardace 10mg Capsule

Basic Information

• Brand Name: Cardace 10mg Capsule

• Generic Name: Ramipril

• Strength: 10 mg

• Category: Antihypertensive / ACE Inhibitor

• Manufacturer: Sanofi India Ltd.

• Prescription Required: Yes (Rx)

Composition

Each capsule contains:

• Ramipril 10 mg

Uses / Indications

Cardace 10mg Capsule is prescribed for:

• Hypertension (High Blood Pressure) – for patients not adequately controlled with lower doses (2.5mg/5mg).

• Heart Failure – improves survival and reduces hospitalizations.

• Post-Myocardial Infarction (after heart attack) – lowers the risk of recurrence and complications.

• Long-term prevention of stroke, kidney disease, and cardiovascular events in high-risk patients (e.g., diabetes, chronic kidney disease, coronary artery disease).

Mechanism of Action

• Ramipril is an ACE Inhibitor (Angiotensin-Converting Enzyme Inhibitor).

• Inhibits conversion of angiotensin I to angiotensin II → prevents narrowing of blood vessels.

• Relaxes and widens arteries → lowers blood pressure.

• Reduces workload on the heart, improves blood flow, and protects kidneys.

Dosage & Administration

• Usual adult dose: 2.5–10 mg once daily (can be divided if needed).

• 10 mg daily is typically the maximum recommended dose.

• Dose should be individualized based on blood pressure and response.

• Can be taken with or without food.

• Take at the same time each day.

• Do not stop suddenly without medical advice.

Side Effects

Common side effects:

• Dizziness, headache

• Dry cough (common with ACE inhibitors)

• Weakness, fatigue

• Nausea, stomach upset

Serious but rare:

• Very low blood pressure (hypotension)

• High potassium levels (hyperkalemia)

• Kidney impairment

• Angioedema (severe swelling of face/throat – medical emergency)

Precautions & Warnings

• Use with caution in patients with:

  • Kidney or liver problems

  • Heart failure

  • Electrolyte imbalance (high potassium)

• Not safe during pregnancy or breastfeeding.

• Avoid alcohol (may worsen dizziness).

• Regular monitoring of blood pressure, potassium levels, and kidney function is advised.

Drug Interactions

• Other antihypertensive medicines (additive effect)

• Potassium supplements / potassium-sparing diuretics

• NSAIDs (ibuprofen, diclofenac – may reduce effect & damage kidneys)

• Lithium (risk of toxicity)

Storage

• Store below 30°C in a cool, dry place.

• Protect from sunlight & moisture.

• Keep out of children’s reach.