Cefakind-CV 500 Tablet

Basic Information

• Brand Name: Cefakind-CV 500 Tablet

• Type: Antibiotic (Cephalosporin + Beta-lactamase Inhibitor)

• Form: Tablet

• Pack Size: Strip of 6 / 10 tablets (commonly available)

• Manufacturer / Marketer: Mankind Pharma Ltd.

Composition (per tablet)

• Cefuroxime Axetil – 500 mg

• Clavulanic Acid – 125 mg

Uses / Indications

Cefakind-CV 500 Tablet is prescribed for moderate to severe bacterial infections, including:

• Respiratory tract infections: pneumonia, bronchitis, sinusitis, tonsillitis, pharyngitis

• ENT infections – otitis media, sinus infections, throat infections

• Urinary tract infections (UTI) – cystitis, pyelonephritis

• Skin & soft tissue infections: cellulitis, abscesses, wound infections

• Bone & joint infections

• Post-operative infections

• Mixed bacterial infections resistant to cephalosporins alone

Mechanism of Action

• Cefuroxime (Cephalosporin antibiotic): Inhibits bacterial cell wall synthesis → causes bacterial lysis & death (bactericidal)

• Clavulanic Acid (Beta-lactamase inhibitor): Blocks bacterial enzymes (beta-lactamases) that cause resistance → makes cefuroxime more effective

• Combined Effect: Broad-spectrum activity, even against resistant bacteria

Dosage & Administration

• Adults: 1 tablet twice daily, or as prescribed by doctor

• Children (>12 years): Dose depends on body weight; pediatric suspensions preferred for younger children

• Best taken after meals for better absorption

• Duration: usually 7–14 days, depending on infection type

Side Effects

• Common: nausea, diarrhea, stomach pain, headache

• Rare: rash, dizziness, oral thrush, vaginal yeast infection

• Severe (rare): allergic reactions, Clostridium difficile–associated diarrhea, liver enzyme changes

Precautions & Warnings

• Use only on doctor’s prescription

• Avoid if allergic to cephalosporins, penicillins, or clavulanic acid

• Use cautiously in patients with liver or kidney impairment

• May interact with anticoagulants (like warfarin)

• Pregnant & breastfeeding women: safe if prescrib