Danogen Forte Capsule

Brand Name

Danogen Forte

Generic Name / Composition

Danazol 200 mg
(Some brands of Danogen Forte are also available in 200 mg and 400 mg strength — confirm pack strength while dispensing)

Main Category

• Synthetic Androgen / Antigonadotropic Agent
  (Hormonal therapy – gynecological & hematological use)

Uses / Indications

• Gynecological Conditions

  • Endometriosis (relieves pelvic pain, suppresses endometrial tissue growth)

  • Fibrocystic breast disease (benign breast pain & nodularity)

  • Menorrhagia (off-label use for heavy menstrual bleeding)

• Hematological / Immunological Disorders

  • Hereditary angioedema (to prevent swelling attacks)

  • Sometimes used in idiopathic thrombocytopenic purpura (ITP) – specialist guidance only

Dosage (General Guidance)

(As per physician’s direction)

• Endometriosis: 200–800 mg/day in divided doses for 3–6 months

• Fibrocystic breast disease: 100–400 mg/day in divided doses

• Hereditary angioedema: 200 mg two to three times daily initially, then maintenance 200 mg/day

Route: Oral

Side Effects

• Weight gain, acne, oily skin

• Hoarseness or deepening of voice (may be permanent)

• Hirsutism (unwanted hair growth)

• Menstrual disturbances (amenorrhea, irregular cycles)

• Mood changes, headache

• Rare: Liver dysfunction, thromboembolic events

Precautions / Warnings

• Contraindicated in pregnancy, breastfeeding, severe liver/kidney/heart disease, androgen-dependent tumors

• May cause virilization in women (monitor for voice changes, hair growth)

• Long-term therapy requires monitoring of liver function & lipid profile

• Use with caution in diabetic patients (may alter blood sugar control)

• Not recommended in children except in hereditary angioedema under specialist supervision

Drug Interactions

• Warfarin (↑ anticoagulant effect, bleeding risk)

• Carbamazepine, Cyclosporine, Statins (↑ toxicity)

• Insulin / oral antidiabetic agents (may affect glucose control)

Packaging

• Strip of 10 capsules (commonly 200 mg strength; Forte version often denotes higher dose)

Manufacturer