Forxiga 10 mg Tablet

Generic Name: Dapagliflozin 10 mg
Category: Oral Anti-Diabetic (SGLT2 Inhibitor)

Description:

Forxiga 10 mg Tablet is an oral anti-diabetic medicine used to manage Type 2 Diabetes Mellitus. It contains Dapagliflozin, which belongs to the class of SGLT2 inhibitors (Sodium-Glucose Co-Transporter 2 inhibitors).

It works by blocking the SGLT2 protein in the kidneys, preventing reabsorption of glucose into the blood and promoting its excretion through urine. This helps lower blood sugar levels, reduce weight, and improve glycemic control.

Forxiga is also prescribed for heart failure and chronic kidney disease (CKD), as it helps protect the heart and kidneys in addition to controlling diabetes.

Uses:

• Type 2 Diabetes Mellitus (to improve blood sugar control)

• Heart Failure (with reduced or preserved ejection fraction)

• Chronic Kidney Disease (CKD) – to slow disease progression

• Reduce risk of cardiovascular complications in patients with diabetes and heart disease

Mechanism of Action:

• Inhibits SGLT2 transporter in the proximal tubules of kidneys

• Increases urinary glucose excretion (glycosuria)

• Lowers blood sugar, reduces HbA1c levels

• Promotes modest weight loss and blood pressure reduction

• Provides cardio-renal protective effects

Dosage & Administration:

• Recommended dose: 10 mg once daily

• Can be taken with or without food

• Maintain adequate hydration to avoid dehydration

• Doctor may adjust dose based on kidney function and overall condition

Common Side Effects:

• Increased urination

• Genital fungal infections (yeast infection, thrush)

• Urinary tract infections (UTI)

• Thirst, dehydration

• Low blood pressure, dizziness

Serious Side Effects (rare):

• Diabetic Ketoacidosis (DKA) – nausea, vomiting, abdominal pain, rapid breathing, confusion

• Severe urinary tract infections (pyelonephritis, urosepsis)

• Fournier’s gangrene (rare but serious genital infection)

• Kidney problems in some cases

Warnings & Precautions:

• Not for Type 1 Diabetes or diabetic ketoacidosis

• Use cautiously in patients with kidney disease, frequent UTIs, or dehydration

• Avoid excessive alcohol intake (risk of ketoacidosis increases)

• Monitor blood sugar, kidney function, and hydration status regularly

• Maintain personal hygiene to prevent genital infections