Galvus 50 mg Tablet

Generic Name: Vildagliptin 50 mg
Category: Oral Anti-Diabetic (DPP-4 Inhibitor)

Description:

Galvus 50 mg Tablet is an oral anti-diabetic medicine used to manage Type 2 Diabetes Mellitus in adults. It contains Vildagliptin, which belongs to the class of DPP-4 inhibitors (Dipeptidyl Peptidase-4 inhibitors).

It helps lower blood sugar by increasing incretin hormone levels. Incretins stimulate the pancreas to release insulin only when blood sugar is high and reduce glucose production by the liver. This dual action improves blood sugar control both after meals and during fasting.

Galvus can be prescribed alone or in combination with other anti-diabetic medicines such as Metformin, Sulfonylureas, Thiazolidinediones, or Insulin.

Uses:

• Management of Type 2 Diabetes Mellitus in adults

• Prevention of complications like kidney damage, nerve problems, eye damage, heart attack, and stroke

Mechanism of Action:

• Inhibits the DPP-4 enzyme

• Increases incretin hormones (GLP-1, GIP)

• Enhances glucose-dependent insulin secretion from the pancreas

• Suppresses excess hepatic (liver) glucose production

• Provides balanced blood sugar control with a low risk of hypoglycemia

Dosage & Administration:

• Typical dose: 50 mg once or twice daily, depending on doctor’s advice

• Can be taken with or without food

• Dose adjustment may be needed in patients with kidney impairment

• Swallow tablet whole with water

Common Side Effects:

• Headache, dizziness

• Constipation or stomach discomfort

• Fatigue

• Cold, sore throat, or mild infections

Serious Side Effects (rare):

• Pancreatitis (severe abdominal pain, nausea, vomiting)

• Liver dysfunction (yellowing of skin/eyes, dark urine)

• Allergic reactions (rash, itching, swelling, difficulty breathing)

• Severe joint pain (rare)

Warnings & Precautions:

• Not for Type 1 Diabetes or diabetic ketoacidosis

• Use cautiously in patients with liver or kidney disease

• Regular monitoring of blood glucose, HbA1c, and liver function is recommended

• Low risk of hypoglycemia when used alone, but risk increases with insulin or sulfonylureas

• Avoid excess alcohol intake