Glimestar PM1 Tablet

GENERIC COMPOSITION:

• Glimepiride 1 mg

• Metformin Hydrochloride 500 mg

• Pioglitazone  15mg

Category: Oral Anti-Diabetic

DESCRIPTION:

Glimestar PM1 Tablet is a combination medicine used to manage Type 2 Diabetes Mellitus.
It contains Glimepiride, which stimulates insulin release, and Metformin, which reduces liver glucose production and improves insulin sensitivity.
Together, they help control fasting and post-meal blood sugar and prevent long-term diabetic complications.

USES:

• Treat Type 2 Diabetes when diet, exercise, or single therapy is insufficient

• Reduce risk of kidney, eye, nerve, and heart complications

MECHANISM OF ACTION:

• Glimepiride: Stimulates pancreas to release insulin

• Metformin: Reduces liver glucose, slows intestinal sugar absorption, improves insulin sensitivity

• Combined effect: Controls fasting and post-meal glucose effectively

DOSAGE & ADMINISTRATION:

• 1 tablet once or twice daily with meals (as prescribed)

• Swallow whole with water; do not crush or chew

• Regular monitoring of blood sugar and HbA1c is recommended

COMMON SIDE EFFECTS:

• Hypoglycemia – sweating, shakiness, dizziness

• Nausea, diarrhea, abdominal discomfort

• Headache, weakness

• Weight gain (possible with Glimepiride)

SERIOUS SIDE EFFECTS (RARE):

• Lactic acidosis (muscle pain, fatigue, breathing difficulty)

• Severe hypoglycemia

• Liver dysfunction (yellow eyes/skin, dark urine)

• Allergic reactions (rash, swelling, difficulty breathing)

WARNINGS & PRECAUTIONS:

• Not for Type 1 Diabetes or diabetic ketoacidosis

• Avoid in severe kidney/liver disease

• Use cautiously in elderly and heart patients

• Avoid alcohol

• Monitor blood sugar, kidney, and liver function regularly