Glimiprex-M1 Tablet

Brand Name

Glimiprex-M1

Generic Name / Composition

• Glimepiride 1 mg (Sulfonylurea – Insulin secretagogue)

• Metformin Hydrochloride 500 mg (Biguanide – Insulin sensitizer)

Main Category

• Antidiabetic Combination (Sulfonylurea + Biguanide)

Description

Glimiprex-M1 Tablet is a combination antidiabetic medicine containing Glimepiride and Metformin.

• Glimepiride stimulates the pancreas to release more insulin.

• Metformin decreases glucose production in the liver and improves insulin sensitivity.

Together, they provide better blood sugar control in Type 2 Diabetes Mellitus patients who are not adequately controlled by diet, exercise, or single-drug therapy.

Uses / Indications

• Management of Type 2 Diabetes Mellitus

• Helps reduce risk of long-term complications like kidney failure, neuropathy, retinopathy, and cardiovascular disease

• Used when monotherapy with Glimepiride or Metformin alone is insufficient

Dosage (General Guidance)

(As prescribed by physician)

• Adults: Usually 1 tablet once or twice daily, with meals

• Dose adjusted depending on blood sugar response

• Must be taken at the same time daily

Route: Oral

Side Effects

• Hypoglycemia (low sugar – sweating, shakiness, dizziness)

• Nausea, vomiting, diarrhea, abdominal discomfort (due to Metformin)

• Headache, weakness

• Rare: Lactic acidosis (serious side effect of Metformin), allergic reactions, liver enzyme changes

Precautions / Warnings

• Not for Type 1 Diabetes or diabetic ketoacidosis

• Avoid excessive alcohol (↑ risk of lactic acidosis with Metformin)

• Risk of hypoglycemia increases with fasting, missed meals, or excess exercise

• Caution in patients with kidney or liver impairment, heart disease

• Requires regular monitoring of blood sugar, kidney function, and HbA1c

Drug Interactions

• Alcohol (↑ risk of lactic acidosis & hypoglycemia)

• Insulin & other antidiabetics (↑ risk of low sugar)

• Steroids, diuretics, thyroid hormones (↓ effectiveness of medicine)

• Certain antibiotics (↑ side effects of Metformin)

Packaging

• Strip of 10 tablets

Manufacturer

Sanofi India Ltd.