Glimiprex-M2 Tablet

Brand Name

Glimiprex-M2

Generic Name / Composition

• Glimepiride 2 mg (Sulfonylurea – Insulin secretagogue)

• Metformin Hydrochloride 500 mg (Biguanide – Insulin sensitizer)

Main Category

• Antidiabetic Combination (Sulfonylurea + Biguanide)

Description

Glimiprex-M2 Tablet is a dual therapy antidiabetic medicine containing Glimepiride and Metformin.

• Glimepiride stimulates the pancreas to release more insulin.

• Metformin lowers glucose production in the liver and improves insulin sensitivity.

This combination helps achieve better glycemic control in patients with Type 2 Diabetes Mellitus, especially when monotherapy is not effective.

Uses / Indications

• Treatment of Type 2 Diabetes Mellitus

• Helps lower fasting and post-meal blood sugar levels

• Reduces long-term risk of diabetic complications (kidney disease, neuropathy, retinopathy, and cardiovascular issues)

• Used in patients who need stronger control than Glimiprex-M1

Dosage (General Guidance)

(As directed by physician)

• Adults: 1 tablet once or twice daily with meals

• Dose adjusted according to blood sugar levels

• Should be taken at the same time daily

Route: Oral

Side Effects

• Hypoglycemia (low blood sugar: sweating, shakiness, dizziness)

• Nausea, diarrhea, stomach upset (due to Metformin)

• Headache, weakness

• Rare: Lactic acidosis (serious but rare with Metformin), allergic reactions, liver enzyme elevation

Precautions / Warnings

• Not for Type 1 Diabetes or diabetic ketoacidosis

• Avoid alcohol (↑ risk of lactic acidosis & hypoglycemia)

• Caution in patients with kidney, liver, or heart problems

• Requires regular monitoring of blood sugar, kidney function, and HbA1c

• Not usually recommended during pregnancy or breastfeeding (insulin preferred)

Drug Interactions

• Alcohol (↑ risk of lactic acidosis & hypoglycemia)

• Insulin & other oral antidiabetics (↑ risk of low blood sugar)

• Steroids, thyroid hormones, diuretics (↓ effect of medicine)

• Certain antibiotics (↑ risk of Metformin side effects)

Packaging

• Strip of 10 tablets

Manufacturer

Sanofi India Ltd.