Gudcef-CV Dry Syrup

Basic Information

• Brand Name: Gudcef-CV Dry Syrup

• Type: Antibiotic (Cephalosporin + β-lactamase inhibitor)

• Form: Dry Syrup (for oral suspension after reconstitution)

• Pack Size: Bottle of 30 ml / 60 ml (with measuring cup/spoon)

• Manufacturer / Marketer: Lupin Ltd.

Composition (per 5 ml reconstituted suspension)

• Cefpodoxime Proxetil – 50 mg

• Clavulanic Acid (as Potassium Clavulanate) – 31.25 mg

Uses / Indications

Gudcef-CV Dry Syrup is prescribed for children to treat bacterial infections such as:

• Respiratory tract infections: pneumonia, bronchitis, tonsillitis, pharyngitis, sinusitis

• ENT infections: otitis media, sinus infections

• Urinary tract infections (UTIs)

• Skin & soft tissue infections (abscess, cellulitis, wound infection)

• Bone & joint infections

Mechanism of Action

• Cefpodoxime (3rd gen cephalosporin): Kills bacteria by inhibiting cell wall synthesis

• Clavulanic Acid: Inhibits β-lactamase enzyme → prevents resistance → enhances cefpodoxime effect

• Combined Effect: Potent against resistant bacterial strains in pediatric infections

Dosage & Administration

• Children: Dose based on body weight (mg/kg/day), usually given every 12 hours as advised by pediatrician

• Reconstitution: Add boiled & cooled water to the dry powder up to the marked line, shake well

• Shake well before each use

• Administer with measuring cup/syringe provided

• Complete full course even if child feels better

Side Effects

• Common: diarrhea, nausea, abdominal pain, mild rash

• Rare: fungal infections, dizziness, liver enzyme elevation

• Severe (rare): persistent diarrhea (C. difficile), jaundice, allergic reaction

Precautions & Warnings

• Use only under pediatrician’s prescription

• Not effective for viral infections (flu, cold)

• Caution in children with liver/kidney disease or history of drug allergy

• Store reconstituted suspension in refrigerator (2–8°C)

• Use within 7–10 days after mixing; discard leftover