Metolar XR 100mg Tablet

Basic Information

• Brand Name: Metolar XR 100mg Tablet

• Generic Name: Metoprolol Succinate (Extended-Release)

• Strength: 100 mg

• Category: Antihypertensive / Beta-Blocker (Cardioselective)

• Manufacturer: Cipla Ltd.

• Prescription Required: Yes (Rx)

Composition

Each extended-release tablet contains:

• Metoprolol Succinate 100 mg (equivalent to Metoprolol Tartrate)

Uses / Indications

Metolar XR 100mg Tablet is prescribed for:

• Hypertension (High Blood Pressure) – moderate to severe cases

• Angina (chest pain due to reduced oxygen to the heart)

• Arrhythmias (irregular heart rhythm)

• Heart Failure (as part of combination therapy, with careful monitoring)

• Post-Myocardial Infarction (heart attack recovery) – improves survival & prevents recurrence

• Migraine prevention (off-label)

• Thyrotoxicosis-related symptoms (off-label)

Mechanism of Action

• Metoprolol is a Beta-1 Selective Blocker.

• Reduces heart rate & pumping force → lowers BP.

• Decreases oxygen demand of the heart → prevents angina.

• Stabilizes abnormal heart rhythms.

• XR (Extended-Release) formulation → maintains steady 24-hour effect with once-daily dosing.

Dosage & Administration

• Usual adult dose: 25–200 mg once daily (depends on condition & patient response).

• 100 mg once daily is a common maintenance dose for hypertension, angina, or arrhythmias.

• Swallow whole with water – do not crush or chew (extended-release formulation).

• Best taken with or after meals for better absorption.

• Do not stop suddenly – may cause rebound hypertension, chest pain, or arrhythmias.

Side Effects

Common side effects:

• Dizziness, tiredness

• Slow heartbeat (bradycardia)

• Cold hands and feet

• Stomach upset, nausea

• Sleep disturbances

Serious but rare:

• Very low heart rate or blood pressure

• Worsening of heart failure

• Breathing difficulty (rare, in asthma/COPD)

• Mood changes, depression

Precautions & Warnings

• Use with caution in patients with:

  • Heart block or severe bradycardia

  • Heart failure (unless carefully monitored)

  • Asthma/COPD (safer than non-selective beta-blockers, but caution advised)

  • Kidney or liver disease

• Not recommended in pregnancy or breastfeeding unless prescribed.

• Avoid alcohol (can worsen dizziness or drowsiness).

• Regular monitoring of BP, heart rate, and heart function is necessary.

Drug Interactions

• Other antihypertensives (additive BP-lowering effect)

• Antiarrhythmics (amiodarone, digoxin – risk of bradycardia)

• Insulin/antidiabetic medicines (may mask hypoglycemia signs)

• NSAIDs (may reduce BP-lowering effect)

Storage

• Store below 30°C in a dry, cool place.

• Protect from moisture & direct sunlight.

• Keep out of children’s reach.