Metolar XR 50mg Tablet

Basic Information

• Brand Name: Metolar XR 50mg Tablet

• Generic Name: Metoprolol Succinate (Extended-Release)

• Strength: 50 mg

• Category: Antihypertensive / Beta-Blocker (Cardioselective)

• Manufacturer: Cipla Ltd.

• Prescription Required: Yes (Rx)

Composition

Each extended-release tablet contains:

• Metoprolol Succinate 50 mg (equivalent to Metoprolol Tartrate)

Uses / Indications

Metolar XR 50mg Tablet is prescribed for:

• Hypertension (High Blood Pressure)

• Angina (chest pain from reduced oxygen supply to the heart)

• Arrhythmias (irregular heartbeat)

• Heart Failure (as part of combination therapy)

• Heart Attack (Myocardial Infarction) – prevention of recurrence & improved survival

• Migraine prevention (off-label use)

• Thyrotoxicosis (symptomatic relief) – off-label

Mechanism of Action

• Metoprolol is a Beta-1 Selective Blocker.

• Lowers heart rate, cardiac output, and workload → reduces BP.

• Improves oxygen balance in the heart → prevents angina.

• Stabilizes heart rhythm and protects after heart attack.

• XR (Extended-Release) formulation → provides 24-hour effect with once-daily dosing.

Dosage & Administration

• Usual adult dose: 25–200 mg once daily (depending on condition).

• 50 mg once daily is a common starting or maintenance dose for hypertension & angina.

• Swallow whole with water – do not crush or chew.

• Take with or immediately after meals.

• Do not stop suddenly – may cause rebound hypertension, angina, or arrhythmias.

Side Effects

Common side effects:

• Dizziness, fatigue

• Slow heartbeat (bradycardia)

• Cold hands/feet

• Nausea, stomach upset

• Sleep disturbance

Serious but rare:

• Severe bradycardia or hypotension

• Worsening heart failure

• Breathing difficulty (rare, in asthma/COPD)

• Mood changes, depression

Precautions & Warnings

• Use with caution in:

  • Heart block or severe bradycardia

  • Heart failure (unless closely monitored)

  • Asthma or COPD (though cardioselective, caution required)

  • Kidney or liver impairment

• Not recommended during pregnancy or breastfeeding unless advised.

• Avoid alcohol (increases drowsiness/dizziness).

• Regular monitoring of BP and heart rate is needed.

Drug Interactions

• Other antihypertensives (extra BP lowering)

• Antiarrhythmics (amiodarone, digoxin – risk of bradycardia)

• Insulin/antidiabetic drugs (may mask low blood sugar symptoms)

• NSAIDs (reduce BP-lowering effect)

Storage

• Store below 30°C in a cool, dry place.

• Protect from light & moisture.

• Keep out of children’s reach.