Metrogyl 400 Tablet

Brand Name

Metrogyl

Generic Name

Metronidazole 400 mg

Main Category

• Antiprotozoal & Antianaerobic Agent
  (Nitroimidazole derivative – not a typical antibiotic)

Uses / Indications

• Amoebiasis (intestinal & extra-intestinal, incl. liver abscess)

• Giardiasis

• Trichomoniasis

• Dental infections (gingivitis, periapical abscess, periodontitis)

• Intra-abdominal infections (peritonitis, abscess)

• Pelvic infections (endometritis, tubo-ovarian abscess, vaginal vault sepsis)

• Skin, soft tissue, bone & joint anaerobic infections

• Bacterial vaginosis

• Surgical prophylaxis (colorectal, gynecological, abdominal procedures)

• H. pylori eradication (as part of combination therapy)

Dosage (General Guidance)

(As per physician’s advice)

• Adults: 400–800 mg every 8–12 hrs

• Amoebiasis: 800 mg TDS for 5–10 days

• Trichomoniasis: 2 g single dose or divided doses

• Children: 20–30 mg/kg/day in divided doses

Route: Oral
Advice: Best taken after meals to reduce gastric upset

Side Effects

• Nausea, vomiting, abdominal pain

• Metallic/bitter taste

• Headache, dizziness

• Dry mouth, dark urine (harmless)

• Rare: Peripheral neuropathy, seizures, allergic reactions, leukopenia

Precautions / Warnings

• Strictly avoid alcohol during treatment & 48 hrs after (causes disulfiram-like reaction)

• Caution in liver & kidney impairment (dose adjustment may be needed)

• Avoid in first trimester of pregnancy unless essential

• Enters breast milk – consult doctor if breastfeeding

• Use with caution in patients with neurological disorders

Packaging

• Blister strip of 10 tablets

Manufacturer

J.B. Chemicals & Pharmaceuticals Ltd.
Neelam Centre, Hind Cycle Road, Worli, Mumbai, India