Mikacin 1 gm Injection

Brand Name: Mikacin 1 gm Injection
Composition: Amikacin Sulphate 1000 mg
Form: Injection (IV/IM use)
Manufacturer: Aristo Pharmaceuticals Pvt. Ltd. 
Category: Antibiotic

Product Overview

Mikacin 1 gm Injection contains Amikacin, a broad-spectrum aminoglycoside antibiotic. It is widely prescribed for the management of serious bacterial infections that do not respond to common antibiotics. Amikacin works by blocking bacterial protein synthesis, which destroys harmful bacteria and controls infection spread.

This higher strength (1 gm) is usually reserved for severe infections and in cases where stronger antibiotic coverage is required, especially in hospital-acquired infections.

Key Benefits

• Strong antibiotic for serious bacterial infections

• Effective in gram-negative and resistant infections

• Useful in severe hospital-acquired and post-surgical infections

• Helps treat infections of lungs, abdomen, urinary tract, skin, bones, and blood

Indications (Uses)

• Severe respiratory tract infections (pneumonia, bronchitis)

• Complicated urinary tract infections (UTIs)

• Intra-abdominal infections (peritonitis, post-surgery)

• Septicemia (bloodstream infection)

• Bone and joint infections

• Skin and soft tissue infections

• Hospital-acquired infections

• Resistant gram-negative infections

Dosage & Administration

• Adults: As prescribed by the physician depending on infection severity and patient’s kidney function

• Route: Intravenous (IV) infusion/slow injection or deep intramuscular (IM) injection
  👉 Must be administered by a trained healthcare professional.

Possible Side Effects

• Pain, redness, or swelling at injection site

• Nausea, vomiting, diarrhea

• Headache, dizziness

• Fever, skin rash, itching

• Rare but serious: kidney damage, hearing loss, balance issues (with prolonged or high doses)

Precautions

• Not suitable for patients allergic to aminoglycosides (gentamicin, tobramycin, amikacin)

• Use cautiously in patients with kidney impairment or ear problems

• Long-term use requires monitoring of kidney function and hearing tests

• Safe during pregnancy/lactation only if clearly prescribed by doctor

Drug Interactions

• Loop diuretics (like furosemide) – may increase risk of hearing loss

• Other nephrotoxic drugs (vancomycin, cephalosporins) – higher risk of kidney damage

• Muscle relaxants – may increase neuromuscular weakness

Storage Instructions

• Store below 25°C in a cool, dry place

• Protect from direct light and moisture

• Use freshly prepared/reconstituted solution immediately or as directed

• Keep out of reach of children