Brand Name: Mikacin 250 Injection
Composition: Amikacin Sulphate 250 mg
Form: Injection (IV/IM use)
Manufacturer: Aristo Pharmaceuticals Pvt. Ltd.
Category: Antibiotic
Product Overview
Mikacin 250 Injection contains Amikacin, an aminoglycoside antibiotic widely used to treat moderate to severe bacterial infections. It works by stopping bacterial protein synthesis, which kills the bacteria and controls the infection.
It is commonly prescribed in respiratory infections, urinary tract infections, abdominal infections, skin and bone infections, septicemia, and hospital-acquired infections.
Key Benefits
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Effective against gram-negative bacterial infections
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Useful in serious infections not responding to other antibiotics
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Works well in hospital-acquired and resistant infections
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Can be used in both adults and children under medical supervision
Indications (Uses)
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Respiratory tract infections (pneumonia, bronchitis)
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Urinary tract infections (UTIs)
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Intra-abdominal infections (peritonitis, post-surgical infections)
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Septicemia (bloodstream infection)
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Bone and joint infections
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Skin and soft tissue infections
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Hospital-acquired infections
Dosage & Administration
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Adults: Dose depends on severity of infection and patient’s condition
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Route: Intravenous (IV) infusion/slow injection or deep intramuscular (IM) injection
👉 Must be administered only by a healthcare professional. Dosage and duration to be decided by the doctor.
Possible Side Effects
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Pain or swelling at injection site
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Nausea, vomiting
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Rash, fever
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Headache, dizziness
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Rare: kidney damage, hearing loss, balance problems (with prolonged/high doses)
Precautions
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Avoid if allergic to aminoglycosides (amikacin, gentamicin, tobramycin)
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Use with caution in patients with kidney problems or hearing issues
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Regular kidney function and hearing tests may be required during long treatment
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Safe in pregnancy/lactation only if prescribed by doctor
Drug Interactions
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Diuretics (like furosemide) – may increase ear/kidney side effects
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Other antibiotics (vancomycin, cephalosporins) – may increase toxicity risk
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Muscle relaxants – may enhance neuromuscular weakness
Storage Instructions
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Store below 25°C in a cool, dry place
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Protect from direct sunlight and moisture
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Keep out of reach of children
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Use reconstituted solution immediately or as per medical advice
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