Monocef-SB 1 gm Injection

Brand Name: Monocef SB 1 gm Injection
Composition: Ceftriaxone 1000 mg + Sulbactam 500 mg
Form: Injection (IV/IM use)
Manufacturer: Aristo Pharmaceuticals Pvt. Ltd.
Category: Antibiotic

Product Overview

Monocef SB 1 gm Injection is a broad-spectrum antibiotic combination containing Ceftriaxone (a third-generation cephalosporin) and Sulbactam (a beta-lactamase inhibitor). This dual action makes it highly effective against a wide variety of bacterial infections, including resistant strains that do not respond to standard antibiotics.

It is prescribed in the treatment of respiratory tract infections, urinary tract infections, abdominal infections, skin infections, bone/joint infections, septicemia, meningitis, and post-surgical infections.

Key Benefits

• Broad-spectrum coverage against gram-positive and gram-negative bacteria

• Sulbactam prevents resistance by inactivating beta-lactamase enzymes

• Effective in treating severe and resistant infections

• Helps in quick recovery and prevents spread of infection

Indications (Uses)

• Lower respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections (complicated & uncomplicated)

• Intra-abdominal infections (peritonitis)

• Septicemia (bloodstream infection)

• Bacterial meningitis

• Bone and joint infections

• Skin and soft tissue infections

• Typhoid fever

• Post-operative infections

Dosage & Administration

• Adults: Usual dose is 1–2 g daily, depending on infection severity

• Route: Intravenous (IV) infusion/slow injection or deep intramuscular (IM) injection
  👉 Must be given only by a healthcare professional. Dosage and duration should be decided by the physician.

Possible Side Effects

• Pain, redness, or swelling at injection site

• Nausea, vomiting, diarrhea

• Fever, rash, or itching

• Headache or dizziness

• Rare: severe allergic reactions, blood cell changes, liver/kidney disturbances

Precautions

• Do not use in patients allergic to cephalosporins, penicillins, or beta-lactam antibiotics

• Caution in patients with kidney or liver disease

• Safe in pregnancy/lactation only if advised by doctor

• Complete the prescribed course to avoid antibiotic resistance

Drug Interactions

• Anticoagulants (blood thinners) – may increase bleeding risk

• Calcium-containing IV solutions – avoid mixing with ceftriaxone

• Aminoglycosides – may increase kidney side effects

Storage Instructions

• Store below 25°C in a cool, dry place

• Protect from light and moisture

• Use reconstituted solution immediately or as directed

• Keep away from children

✅ Quick Info (Short Description)