Brand Name: Monocef SB 250 Injection
Composition: Ceftriaxone 250 mg + Sulbactam 125 mg
Form: Injection (IM/IV use)
Manufacturer: Aristo Pharmaceuticals Pvt. Ltd.
Category: Antibiotic
Product Overview
Monocef SB 250 Injection is a combination antibiotic that contains Ceftriaxone, a third-generation cephalosporin, and Sulbactam, a beta-lactamase inhibitor. Ceftriaxone fights bacterial infections by destroying their cell wall, while Sulbactam prevents bacterial resistance, making the combination more effective against tough and resistant infections.
It is commonly prescribed for respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, bone/joint infections, and post-surgical infections.
Key Benefits
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Effective against a wide range of bacterial infections
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Dual action: Ceftriaxone kills bacteria, Sulbactam prevents resistance
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Useful in children and adults for moderate infections
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Provides faster recovery in resistant infections
Indications (Uses)
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Respiratory tract infections (pneumonia, bronchitis)
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Urinary tract infections (UTIs)
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Intra-abdominal infections (peritonitis)
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Septicemia (blood infections)
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Meningitis (brain infection)
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Bone and joint infections
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Typhoid fever
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Skin and soft tissue infections
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Post-operative infections
Dosage & Administration
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Adults & Children: Dose depends on age, weight, and infection severity
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Route: Intramuscular (IM) or Intravenous (IV) injection only
👉 Must be administered by a qualified healthcare professional. Dosage and duration strictly as prescribed by the doctor.
Possible Side Effects
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Pain, redness, or swelling at injection site
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Nausea, vomiting, diarrhea
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Rash, itching, or mild fever
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Headache, dizziness
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Rare: severe allergic reactions, blood count changes, liver/kidney disturbances
Precautions
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Not recommended in patients allergic to cephalosporins, penicillins, or beta-lactam antibiotics
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Use with caution in patients with kidney or liver disease
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Safe in pregnancy/lactation only if prescribed
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Always complete the full course to prevent antibiotic resistance
Drug Interactions
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Anticoagulants (blood thinners) – may increase bleeding tendency
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Calcium-containing IV solutions – should not be mixed with ceftriaxone
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Aminoglycosides and certain antifungals – may increase side effects
Storage Instructions
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Store below 25°C in a cool, dry place
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Protect from direct light and moisture
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Use reconstituted solution immediately or as instructed by physician
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Keep out of reach of children
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