Norflox-TZ RF Tablet

Brand Name

Norflox-TZ RF Tablet

🔹 Composition

Each tablet contains:

• Norfloxacin 400 mg (Fluoroquinolone antibiotic)

• Tinidazole 600 mg (Antiprotozoal & Antibacterial)

🔹 Manufacturer

Cipla Ltd.

🔹 Category

Antibacterial + Antiprotozoal combination

📌 Description

Norflox-TZ RF Tablet is a fixed-dose combination of Norfloxacin and Tinidazole, used mainly for gastrointestinal and genitourinary infections. Norfloxacin fights bacterial infections by inhibiting DNA replication, while Tinidazole kills protozoa and anaerobic bacteria. The RF (Ready Film-Coated) formulation provides improved patient compliance and better gastrointestinal tolerance.

✅ Indications / Uses

Norflox-TZ RF is prescribed for:

• Acute diarrhoea & dysentery (including traveler’s diarrhoea)

• Gastrointestinal infections due to bacteria & protozoa

• Urinary tract infections (UTIs)

• Gynecological infections (bacterial vaginosis, trichomoniasis)

• Mixed bacterial and protozoal infections

⚠️ Not effective against viral infections.

💊 Dosage & Administration

• Usual adult dose: One tablet twice daily (morning and evening), or as prescribed.

• Best taken after food with a glass of water.

• Avoid alcohol during therapy and up to 72 hours after stopping (due to tinidazole).

• Complete the full prescribed course even if symptoms improve early.

⚠️ Side Effects

Common:

• Nausea, vomiting

• Stomach pain, bloating, diarrhoea

• Metallic taste in mouth

• Headache, dizziness

Serious (rare):

• Allergic reaction (rash, swelling, difficulty breathing)

• Tendon rupture (with norfloxacin, more likely in elderly)

• Nerve problems (tingling, numbness)

• Liver issues (jaundice, dark urine)

⚠️ Precautions & Warnings

• Contraindicated in patients allergic to fluoroquinolones or nitroimidazoles.

• Strictly avoid alcohol during and for at least 72 hours after therapy.

• Use with caution in patients with liver disease, kidney problems, epilepsy, or tendon disorders.

• Not recommended during pregnancy or breastfeeding unless prescribed.

• May interact with antacids, iron, zinc supplements, warfarin, theophylline, and multivitamins.

📦 Storage

• Store at room temperature below 30°C.

• Protect from light and moisture.

• Keep out of reach of children.

🏷️ Key Highlights

• Dual-action therapy (antibiotic + antiprotozoal)

• Effective for diarrhoea, dysentery, UTIs, and gynecological infections

• RF film-coated formulation ensures better tolerance