Basic Information
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Brand Name: Olmezest 40mg Tablet
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Generic Name: Olmesartan Medoxomil
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Strength: 40 mg
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Category: Antihypertensive / Angiotensin II Receptor Blocker (ARB)
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Manufacturer: Sun Pharmaceutical Industries Ltd.
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Prescription Required: Yes (Rx)
Composition
Each tablet contains:
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Olmesartan Medoxomil 40 mg
Uses / Indications
Olmezest 40mg Tablet is prescribed for:
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Hypertension (High Blood Pressure) – for patients not controlled on 20 mg.
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Reduces the risk of heart attack, stroke, and kidney complications caused by high BP.
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Provides kidney protection in patients with Type 2 Diabetes and hypertension.
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Can be used alone or in combination with other BP medicines like diuretics or calcium channel blockers.
Mechanism of Action
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Olmesartan belongs to the class Angiotensin II Receptor Blockers (ARBs).
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It blocks angiotensin II hormone → prevents narrowing of blood vessels.
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Relaxes and widens arteries → lowers blood pressure.
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Improves blood flow and reduces workload on the heart.
Dosage & Administration
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Usual adult dose: 20–40 mg once daily.
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40 mg daily is the maximum recommended dose.
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Can be taken with or without food.
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Take at the same time every day.
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Do not discontinue suddenly without consulting your doctor.
Side Effects
Common side effects:
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Dizziness, headache
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Tiredness, weakness
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Stomach upset, diarrhea
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Muscle or joint pain
Serious but rare:
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Severe low blood pressure
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High potassium levels (hyperkalemia)
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Kidney function impairment
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Severe allergic reaction (rash, swelling, difficulty breathing)
Precautions & Warnings
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Use carefully in patients with:
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Kidney or liver disease
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Heart failure
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Electrolyte imbalance (high potassium)
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Not recommended during pregnancy or breastfeeding.
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Avoid alcohol (may worsen dizziness).
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Monitor blood pressure, kidney function, and potassium regularly.
Drug Interactions
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Other antihypertensives (additive effect)
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Potassium supplements / potassium-sparing diuretics
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NSAIDs (ibuprofen, diclofenac – may reduce effectiveness & affect kidneys)
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Lithium (increased toxicity risk)
Storage
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Store in a cool, dry place below 30°C.
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Protect from direct sunlight & moisture.
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Keep out of children’s reach
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