Olmezest-AM 20/5 Tablet

Basic Information

• Brand Name: Olmezest-AM 20/5 Tablet

• Generic Name: Olmesartan + Amlodipine

• Strength: Olmesartan 20 mg + Amlodipine 5 mg

• Category: Antihypertensive (ARB + Calcium Channel Blocker)

• Manufacturer: Sun Pharmaceutical Industries Ltd.

• Prescription Required: Yes (Rx)

Composition

Each tablet contains:

• Olmesartan Medoxomil 20 mg (Angiotensin II Receptor Blocker – ARB)

• Amlodipine 5 mg (Calcium Channel Blocker – CCB)

Uses / Indications

Olmezest-AM 20/5 Tablet is prescribed for:

• Hypertension (High Blood Pressure) – when single medicine is not enough.

• Reducing risk of stroke, heart attack, and kidney complications caused by high BP.

• Effective in patients with Type 2 Diabetes and hypertension for cardiovascular protection.

Mechanism of Action

• Olmesartan (ARB): Blocks angiotensin II → prevents blood vessel constriction → lowers BP.

• Amlodipine (CCB): Relaxes and dilates arteries by blocking calcium entry → improves blood flow & reduces heart’s workload.

• Together they give dual action for stronger and longer blood pressure control.

Dosage & Administration

• Usual adult dose: 1 tablet once daily.

• Take at the same time each day.

• Can be taken with or without food.

• Do not stop without consulting your doctor.

Side Effects

Common side effects:

• Dizziness, headache

• Swelling of ankles/feet (from Amlodipine)

• Fatigue, weakness

• Stomach upset, flushing

Serious but rare:

• Severe low BP

• High potassium (from Olmesartan)

• Kidney impairment

• Allergic reaction (rash, swelling, breathing difficulty)

Precautions & Warnings

• Use with caution in patients with:

  • Kidney or liver disease

  • Heart failure or heart rhythm disorders

  • Electrolyte imbalance (high potassium levels)

• Not safe during pregnancy or breastfeeding.

• Avoid alcohol (may worsen dizziness).

• Regular monitoring of BP, kidney function, and electrolytes is important.

Drug Interactions

• Other antihypertensives (extra BP lowering)

• Potassium supplements / potassium-sparing diuretics

• NSAIDs (ibuprofen, diclofenac – may reduce effectiveness & harm kidneys)

• Lithium (risk of toxicity)

Storage

• Store below 30°C in a dry place.

• Protect from sunlight & moisture.

• Keep away from children.