Ramace 2.5mg Capsule

Basic Information

• Brand Name: Ramace 2.5mg Capsule

• Generic Name: Ramipril

• Strength: 2.5 mg

• Category: Antihypertensive / ACE Inhibitor

• Manufacturer: Cadila Pharmaceuticals Ltd.

• Prescription Required: Yes (Rx)

Composition

Each capsule contains:

• Ramipril 2.5 mg

Uses / Indications

Ramace 2.5mg Capsule is prescribed for:

• Hypertension (High Blood Pressure) – lowers and maintains blood pressure.

• Heart Failure – improves symptoms and survival.

• Post-Myocardial Infarction (after heart attack) – prevents recurrence and reduces complications.

• Long-term prevention of stroke, kidney disease, and cardiovascular events in high-risk patients (e.g., diabetes, chronic kidney disease, coronary artery disease).

Mechanism of Action

• Ramipril is an ACE Inhibitor (Angiotensin-Converting Enzyme Inhibitor).

• Inhibits conversion of angiotensin I to angiotensin II → prevents narrowing of blood vessels.

• Relaxes and dilates arteries → lowers blood pressure.

• Improves blood circulation, reduces strain on the heart, and protects kidneys.

Dosage & Administration

• Usual adult dose: 2.5–10 mg daily.

• 2.5 mg once daily is a common starting dose.

• Dose may be increased gradually depending on blood pressure and response.

• Can be taken with or without food.

• Should be taken at the same time daily.

• Do not stop suddenly without doctor’s advice.

Side Effects

Common side effects:

• Dizziness, headache

• Dry cough (common with ACE inhibitors)

• Fatigue, weakness

• Stomach upset

Serious but rare:

• Very low blood pressure (hypotension)

• High potassium levels (hyperkalemia)

• Impaired kidney function

• Severe allergic reactions (angioedema – swelling of face/throat, medical emergency)

Precautions & Warnings

• Use cautiously in patients with:

  • Kidney or liver impairment

  • Heart failure

  • Electrolyte imbalance (high potassium levels)

• Not safe during pregnancy or breastfeeding.

• Avoid alcohol (may worsen dizziness).

• Regular monitoring of BP, kidney function, and potassium is recommended.

Drug Interactions

• Other antihypertensive medicines

• Potassium supplements / potassium-sparing diuretics

• NSAIDs (ibuprofen, diclofenac – may reduce effect & harm kidneys)

• Lithium (risk of toxicity)

Storage

• Store below 30°C in a cool, dry place.

• Protect from direct sunlight & moisture.

• Keep out of children’s reach.