Xone-S 1.5 g Injection

Brand Name: Xone-S 1.5 g Injection
Composition: Ceftriaxone 1 g + Sulbactam 0.5 g
Dosage Form: Injection (IV/IM)
Manufacturer: Alkem Laboratories Ltd.
Category: Cephalosporin Antibiotic + Beta-lactamase inhibitor

Description: Xone-S 1.5 g Injection is a combination of Ceftriaxone (3rd generation cephalosporin antibiotic) and Sulbactam (beta-lactamase inhibitor). This combination enhances antibacterial activity by killing harmful bacteria and preventing resistance. It is used in treating moderate to severe bacterial infections.

Uses:

• Respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections (UTI)

• Skin & soft tissue infections

• Bone & joint infections

• Abdominal infections (peritonitis, sepsis)

• Meningitis

• Septicemia (blood infections)

• Gynecological and post-operative infections

Dosage & Administration:

• Adults: 1.5–3 g daily in divided doses; severe cases up to 4 g/day.

• Children: 50–75 mg/kg/day (max 2 g/day).

• Route: IV infusion or deep IM injection.
  👉 Dose must be individualized and prescribed by doctor.

Side Effects: Pain/swelling at injection site, diarrhea, nausea, vomiting, rash, mild liver enzyme changes, rare allergic reactions.

Precautions:

• Avoid in patients allergic to cephalosporins/penicillins.

• Use with caution in patients with kidney or liver impairment.

• Safe in pregnancy/lactation only if prescribed by doctor.

Drug Interactions:

• May increase bleeding risk with anticoagulants (warfarin, heparin).

• May interact with aminoglycosides (higher nephrotoxicity risk).

• Avoid mixing with calcium-containing IV solutions (risk of precipitation).

• Inform doctor about all ongoing medicines.

Storage: Store below 25°C, protect from light & moisture. Reconstituted solution should be used immediately or as directed. Keep out of reach of children.